Cargando…

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

The DNA replication machinery invariably encounters obstacles that slow replication fork progression, and threaten to prevent complete replication and faithful segregation of sister chromatids. The resulting replication stress activates ATR, the major kinase involved in resolving impaired DNA replic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kanu, Nnennaya, Zhang, Tianyi, Burrell, Rebecca A., Chakraborty, Atanu, Cronshaw, Janet, Da Costa, Clive, Grönroos, Eva, Pemberton, Helen N., Anderton, Emma, Gonzalez, Laure, Sabbioneda, Simone, Ulrich, Helle D., Swanton, Charles, Behrens, Axel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842010/ https://www.ncbi.nlm.nih.gov/pubmed/26549024 http://dx.doi.org/10.1038/onc.2015.427

Ejemplares similares

Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation
por: Blake, Sophia M, et al.
Publicado: (2016)

ATMIN Is Required for Maintenance of Genomic Stability and Suppression of B Cell Lymphoma
por: Loizou, Joanna I., et al.
Publicado: (2011)

ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress
por: Liu, Rui, et al.
Publicado: (2017)

The role of WRNIP1 in genome maintenance
por: Yoshimura, Akari, et al.
Publicado: (2017)

ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress
por: Schmidt, Luisa, et al.
Publicado: (2014)

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation
por: Prochazkova, Jana, et al.
Publicado: (2015)

WRNIP1 Is Recruited to DNA Interstrand Crosslinks and Promotes Repair
por: Socha, Anna, et al.
Publicado: (2020)

Atmin mediates kidney morphogenesis by modulating Wnt signaling
por: Goggolidou, Paraskevi, et al.
Publicado: (2014)

R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1
por: Marabitti, Veronica, et al.
Publicado: (2022)

ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis
por: Goggolidou, Paraskevi, et al.
Publicado: (2014)

miR‐22 enhances the radiosensitivity of small‐cell lung cancer by targeting the WRNIP1
por: Jiang, Wenhua, et al.
Publicado: (2019)

A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms
por: Szikriszt, Bernadett, et al.
Publicado: (2021)

Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1
por: Leszczynska, Katarzyna B., et al.
Publicado: (2016)

WRNIP1 Protects Reversed DNA Replication Forks from SLX4-Dependent Nucleolytic Cleavage
por: Porebski, Bartlomiej, et al.
Publicado: (2019)

Checkpoint Defects Elicit a WRNIP1-Mediated Response to Counteract R-Loop-Associated Genomic Instability
por: Marabitti, Veronica, et al.
Publicado: (2020)

The Mgs1/WRNIP1 ATPase is required to prevent a recombination salvage pathway at damaged replication forks
por: Jiménez-Martín, Alberto, et al.
Publicado: (2020)

Replication stress links structural and numerical cancer chromosomal instability
por: Burrell, Rebecca A., et al.
Publicado: (2013)

Deciphering the Novel Role of AtMIN7 in Cuticle Formation and Defense against the Bacterial Pathogen Infection
por: Zhao, Zhenzhen, et al.
Publicado: (2020)

Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation
por: Bakr, A., et al.
Publicado: (2015)

MicroRNA-361-5p slows down gliomas development through regulating UBR5 to elevate ATMIN protein expression
por: Jia, Jiaoying, et al.
Publicado: (2021)

A Kinase-Independent Role for the Rad3(ATR)-Rad26(ATRIP) Complex in Recruitment of Tel1(ATM) to Telomeres in Fission Yeast
por: Subramanian, Lakxmi, et al.
Publicado: (2010)

The Genome of the Chicken DT40 Bursal Lymphoma Cell Line
por: Molnár, János, et al.
Publicado: (2014)

Fission Yeast Tel1(ATM) and Rad3(ATR) Promote Telomere Protection and Telomerase Recruitment
por: Moser, Bettina A., et al.
Publicado: (2009)

The ATP-bound conformation of the Mre11–Rad50 complex is essential for Tel1/ATM activation
por: Cassani, Corinne, et al.
Publicado: (2019)

ATM Promotes RAD51-Mediated Meiotic DSB Repair by Inter-Sister-Chromatid Recombination in Arabidopsis
por: Yao, Yuan, et al.
Publicado: (2020)

Association of ATM Gene Polymorphism with PTC Metastasis in Female Patients
por: Gu, Yulu, et al.
Publicado: (2014)

Radioresistance of chordoma cells is associated with the ATM/ATR pathway, in which RAD51 serves as an important downstream effector
por: Zhang, Chao, et al.
Publicado: (2017)

Ataxia-televangelist mutated (ATM)/ ATR serine/threonine kinase (ATR)-mediated RAD51 recombinase (RAD51) promotes osteogenic differentiation and inhibits osteoclastogenesis in osteoporosis
por: Qiu, Minli, et al.
Publicado: (2022)

Research Progress on Postoperative Minimal/Molecular Residual Disease Detection in Lung Cancer
por: Wu, Manqi, et al.
Publicado: (2022)

Mechanistic analysis of PCNA poly-ubiquitylation by the ubiquitin protein ligases Rad18 and Rad5
por: Parker, Joanne L, et al.
Publicado: (2009)

Mre11–Rad50–Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity
por: Jazayeri, Ali, et al.
Publicado: (2008)

Mre11-Rad50–dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1
por: Limbo, Oliver, et al.
Publicado: (2018)

A comprehensive survey of the mutagenic impact of common cancer cytotoxics
por: Szikriszt, Bernadett, et al.
Publicado: (2016)

Double heterozygous mutation in RAD50 and ATM genes in a Peruvian family with five cancer types: a case report
por: Sanchez-Castro, Enrique Eduardo, et al.
Publicado: (2022)

The Pseudomonas syringae pv. tomato Type III Effector HopM1 Suppresses Arabidopsis Defenses Independent of Suppressing Salicylic Acid Signaling and of Targeting AtMIN7
por: Gangadharan, Anju, et al.
Publicado: (2013)

Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling
por: Richards, Taylor, et al.
Publicado: (2019)

Tel1(ATM) and Rad3(ATR) kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast
por: Moser, Bettina A., et al.
Publicado: (2011)

Moderate penetrance genes complicate genetic testing for breast cancer diagnosis: ATM, CHEK2, BARD1 and RAD51D
por: Graffeo, R., et al.
Publicado: (2022)

Reseaux ATM
por: Boisseau, Marc, et al.
Publicado: (1994)

ATM in senescence
por: Aird, Katherine M., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_imivt0d417jjn14a6a30u09s53