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Frequency and distribution of FCN2 and FCN3 functional variants among MBL2 genotypes

The six types of pattern recognition molecules (PRMs) that initiate complement via the lectin pathway (LP) comprise collectins and ficolins. The importance of having various PRMs to initiate the LP is currently unclear. Mannan-binding lectin (MBL) is a collectin member of the LP PRMs. MBL deficiency...

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Detalles Bibliográficos
Autores principales: Bjarnadottir, Helga, Arnardottir, Margret, Ludviksson, Bjorn Runar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842218/
https://www.ncbi.nlm.nih.gov/pubmed/26795763
http://dx.doi.org/10.1007/s00251-016-0903-4