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The Effects of Imatinib Mesylate on Cellular Viability, Platelet Derived Growth Factor and Stem Cell Factor in Mouse Testicular Normal Leydig Cells

BACKGROUND: Growth factors play an essential role in the development of tumor and normal cells like testicular leydig cells. Treatment of cancer with anti-cancer agents like imatinib mesylate may interfere with normal leydig cell activity, growth and fertility through failure in growth factors’ prod...

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Detalles Bibliográficos
Autores principales: Kheradmand, Fatemeh, Hashemnia, Seyyed Mohammad Reza, Valizadeh, Nasim, Roshan-Milani, Shiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842238/
https://www.ncbi.nlm.nih.gov/pubmed/27141462