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Cyclic AMP signaling restricts activation and promotes maturation and antioxidant defenses in astrocytes

BACKGROUND: cAMP signaling produces dramatic changes in astrocyte morphology and physiology. However, its involvement in phenotype acquisition and the transcriptionally mediated mechanisms of action are largely unknown. RESULTS: Here we analyzed the global transcriptome of cultured astroglial cells...

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Detalles Bibliográficos
Autores principales: Paco, Sonia, Hummel, Manuela, Plá, Virginia, Sumoy, Lauro, Aguado, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842285/
https://www.ncbi.nlm.nih.gov/pubmed/27108081
http://dx.doi.org/10.1186/s12864-016-2623-4