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RNA folding with hard and soft constraints

BACKGROUND: A large class of RNA secondary structure prediction programs uses an elaborate energy model grounded in extensive thermodynamic measurements and exact dynamic programming algorithms. External experimental evidence can be in principle be incorporated by means of hard constraints that rest...

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Detalles Bibliográficos
Autores principales: Lorenz, Ronny, Hofacker, Ivo L., Stadler, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842303/
https://www.ncbi.nlm.nih.gov/pubmed/27110276
http://dx.doi.org/10.1186/s13015-016-0070-z