Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development

The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that increases the expression of detoxifying enzymes upon ligand stimulation. Recent studies now suggest that novel endogenous roles of the AHR exist throughout development. In an effort to create an optimized model syste...

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Detalles Bibliográficos
Autores principales: Smith, Brenden W., Stanford, Elizabeth A., Sherr, David H., Murphy, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842384/
https://www.ncbi.nlm.nih.gov/pubmed/27148368
http://dx.doi.org/10.1155/2016/2574152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842384/
https://www.ncbi.nlm.nih.gov/pubmed/27148368
http://dx.doi.org/10.1155/2016/2574152

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