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AB157. The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells

OBJECTIVE: Although it was shown that p-nitrophenol is anti-androgenic in vivo, the molecular details of how p-nitrophenol inhibits AR signaling are still not quite clear. In this report, we want to figure out this signaling in human cells. METHODS: (I) Cell viability assay; (II) endogenous expressi...

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Detalles Bibliográficos
Autores principales: Wu, Dan, Wang, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842504/
http://dx.doi.org/10.21037/tau.2016.s157