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AB127. Synthetic Tet-inducible small hairpin RNAs targeting hTERT or Bcl-2 inhibit malignant phenotypes of bladder cancer T24 and 5637 cell

OBJECTIVE: To develop Tet-regulated small hairpin RNA (shRNA) that inhibits the malignant phenotypes of tumor cell through Ribonucleic acid interference (RNAi). METHODS: Here we build a type of tetracycline (Tet)-inducible vectors which can achieve regulatable expression of shRNA in a time-dependent...

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Detalles Bibliográficos
Autores principales: Liu, Yuchen, Lin, Junhao, Huang, Weiren, Cai, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842556/
http://dx.doi.org/10.21037/tau.2016.s127