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AB127. Synthetic Tet-inducible small hairpin RNAs targeting hTERT or Bcl-2 inhibit malignant phenotypes of bladder cancer T24 and 5637 cell
OBJECTIVE: To develop Tet-regulated small hairpin RNA (shRNA) that inhibits the malignant phenotypes of tumor cell through Ribonucleic acid interference (RNAi). METHODS: Here we build a type of tetracycline (Tet)-inducible vectors which can achieve regulatable expression of shRNA in a time-dependent...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842556/ http://dx.doi.org/10.21037/tau.2016.s127 |