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AB268. Down-regulation XIAP expression enhances the sensitivity of RCC cells to apoptosis, but the basal expression of XIAP in apoptosis is stable
BACKGROUND: Dysregulation of apoptotic pathway plays a critical role in tumor progression and resistance to chemo-, immuno- and radio-therapy in human renal cell carcinoma (RCC). The X-linked Inhibitor of Apoptosis (XIAP), a key member of the Inhibitors of Apoptosis Protein (IAP) family, possesses t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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AME Publishing Company
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842595/ http://dx.doi.org/10.21037/tau.2016.s268 |