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AB252. The positive expression of SET8 possesses prognostic relevance and mediates Wnt target gene activation in renal cell carcinoma

BACKGROUND: Renal cell carcinoma (RCC) is common renal malignancy within poor prognosis. Histone methylase SET8 plays vital roles in tumorigenesis through regulating Wnt/β-catenin signaling and other cancer-related pathways. Here, we studied the expression and function of SET8 inccRCC METHODS: Our s...

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Detalles Bibliográficos
Autores principales: Shen, Tianyi, Yi, Xiaoming, Zhou, Wenquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842698/
http://dx.doi.org/10.21037/tau.2016.s252