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AB243. Deep sequencing reveals intensive interindividual and intraindividual heterogeneity in TCR-beta repertoire across multiple renal cell carcinoma subtypes

BACKGROUND: Tumor immunogenicity has been proved to have an essential role in tumor development and metastasis. Cancer cell recognition of T cells can be potentially utilized in tumor prognosis and immunotherapy. However, the understanding of immune responses and T cell receptor (TCR) repertoires in...

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Detalles Bibliográficos
Autor principal: Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842725/
http://dx.doi.org/10.21037/tau.2016.s243