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AB249. 15-oxospiramilactone reverses multidrug resistance in the Human Renal Cell Carcinoma by targeting ABCB1 through Inhibition of Wnt/β-catenin signaling
BACKGROUND: Multidrug resistance (MDR) is the main barrier to the success of chemotherapy for Human Renal Cell Carcinoma. P-glycoprotein ABCB1 plays a major role in MDR of malignant cells and is regulated by various transcription factors, including Wnt/β-catenin /TCF4. We previously reported 15-oxos...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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AME Publishing Company
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842754/ http://dx.doi.org/10.21037/tau.2016.s249 |