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AB249. 15-oxospiramilactone reverses multidrug resistance in the Human Renal Cell Carcinoma by targeting ABCB1 through Inhibition of Wnt/β-catenin signaling

BACKGROUND: Multidrug resistance (MDR) is the main barrier to the success of chemotherapy for Human Renal Cell Carcinoma. P-glycoprotein ABCB1 plays a major role in MDR of malignant cells and is regulated by various transcription factors, including Wnt/β-catenin /TCF4. We previously reported 15-oxos...

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Detalles Bibliográficos
Autores principales:	Shen, Tianyi, Yi, Xiaoming, Zhou, Wenquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2016
Materias:	Printed Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842754/ http://dx.doi.org/10.21037/tau.2016.s249

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