Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous Nephropathy

Membranous nephropathy (MN), a major cause of nephrotic syndrome, is a non-inflammatory immune kidney disease mediated by IgG antibodies that form glomerular subepithelial immune complexes. In primary MN, autoantibodies target proteins expressed on the podocyte surface, often phospholipase A2 recept...

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Detalles Bibliográficos
Autor principal: Borza, Dorin-Bogdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842769/
https://www.ncbi.nlm.nih.gov/pubmed/27199983
http://dx.doi.org/10.3389/fimmu.2016.00157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842769/
https://www.ncbi.nlm.nih.gov/pubmed/27199983
http://dx.doi.org/10.3389/fimmu.2016.00157

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