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One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug

HIGHLIGHTS: Many AD target combinations are being explored for multi-target drug design. New databases and models increase the potential of computational drug design. Liraglutide and other antidiabetics are strong candidates for repurposing to AD. Donecopride a dual 5-HT/AChE inhibitor shows promise...

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Detalles Bibliográficos
Autores principales: Hughes, Rebecca E., Nikolic, Katarina, Ramsay, Rona R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842778/
https://www.ncbi.nlm.nih.gov/pubmed/27199640
http://dx.doi.org/10.3389/fnins.2016.00177