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One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug
HIGHLIGHTS: Many AD target combinations are being explored for multi-target drug design. New databases and models increase the potential of computational drug design. Liraglutide and other antidiabetics are strong candidates for repurposing to AD. Donecopride a dual 5-HT/AChE inhibitor shows promise...
Autores principales: | Hughes, Rebecca E., Nikolic, Katarina, Ramsay, Rona R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842778/ https://www.ncbi.nlm.nih.gov/pubmed/27199640 http://dx.doi.org/10.3389/fnins.2016.00177 |
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