Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan endemic nephropathy, is a regulator of K2P channels

BACKGROUND AND PURPOSE: Aristolochic acid (AristA) is found in plants used in traditional medicines to treat pain. We investigated the action of AristA on TREK and TRESK, potassium (K2P) channels, which are potential therapeutic targets in pain. Balkan endemic nephropathy (BEN) is a renal disease as...

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Detalles Bibliográficos
Autores principales: Veale, Emma L, Mathie, Alistair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842925/
https://www.ncbi.nlm.nih.gov/pubmed/26914156
http://dx.doi.org/10.1111/bph.13465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842925/
https://www.ncbi.nlm.nih.gov/pubmed/26914156
http://dx.doi.org/10.1111/bph.13465

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