Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis

Genotypic variability based genome-wide association studies (vGWASs) can identify potentially interacting loci without prior knowledge of the interacting factors. We report a two-stage approach to make vGWAS applicable to diseases: firstly using a mixed model approach to partition dichotomous phenot...

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Detalles Bibliográficos
Autores principales: Wei, Wen-Hua, Bowes, John, Plant, Darren, Viatte, Sebastien, Yarwood, Annie, Massey, Jonathan, Worthington, Jane, Eyre, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842957/
https://www.ncbi.nlm.nih.gov/pubmed/27109064
http://dx.doi.org/10.1038/srep25014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842957/
https://www.ncbi.nlm.nih.gov/pubmed/27109064
http://dx.doi.org/10.1038/srep25014

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