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Pan-cancer subtyping in a 2D-map shows substructures that are driven by specific combinations of molecular characteristics

The use of genome-wide data in cancer research, for the identification of groups of patients with similar molecular characteristics, has become a standard approach for applications in therapy-response, prognosis-prediction, and drug-development. To progress in these applications, the trend is to mov...

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Detalles Bibliográficos
Autores principales: Taskesen, Erdogan, Huisman, Sjoerd M. H., Mahfouz, Ahmed, Krijthe, Jesse H., de Ridder, Jeroen, van de Stolpe, Anja, van den Akker, Erik, Verheagh, Wim, Reinders, Marcel J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842960/
https://www.ncbi.nlm.nih.gov/pubmed/27109935
http://dx.doi.org/10.1038/srep24949