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Blastomere removal from cleavage-stage mouse embryos alters placental function, which is associated with placental oxidative stress and inflammation

Blastomere biopsy is an essential technique in preimplantation genetic diagnosis (PGD), a screening test that can detect genetic abnormalities of embryos before their transfer into uterus. Our results showed that the weights of fetuses derived from biopsied embryos were lower than that of non-biopsi...

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Detalles Bibliográficos
Autores principales: Yao, Qi, Chen, Li, Liang, Yuanjiao, Sui, Liucai, Guo, Li, Zhou, Jingwei, Fan, Kai, Jing, Jun, Zhang, Yunhai, Yao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842963/
https://www.ncbi.nlm.nih.gov/pubmed/27109212
http://dx.doi.org/10.1038/srep25023