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Exercise capacity and cardiac hemodynamic response in female ApoE/LDLR(−/−) mice: a paradox of preserved V’O(2max) and exercise capacity despite coronary atherosclerosis
We assessed exercise performance, coronary blood flow and cardiac reserve of female ApoE/LDLR(−/−) mice with advanced atherosclerosis compared with age-matched, wild-type C57BL6/J mice. Exercise capacity was assessed as whole body maximal oxygen consumption (V’O(2max)), maximum running velocity (v(m...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842974/ https://www.ncbi.nlm.nih.gov/pubmed/27108697 http://dx.doi.org/10.1038/srep24714 |