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Exercise capacity and cardiac hemodynamic response in female ApoE/LDLR(−/−) mice: a paradox of preserved V’O(2max) and exercise capacity despite coronary atherosclerosis

We assessed exercise performance, coronary blood flow and cardiac reserve of female ApoE/LDLR(−/−) mice with advanced atherosclerosis compared with age-matched, wild-type C57BL6/J mice. Exercise capacity was assessed as whole body maximal oxygen consumption (V’O(2max)), maximum running velocity (v(m...

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Detalles Bibliográficos
Autores principales: Wojewoda, M., Tyrankiewicz, U., Gwozdz, P., Skorka, T., Jablonska, M., Orzylowska, A., Jasinski, K., Jasztal, A., Przyborowski, K., Kostogrys, R. B., Zoladz, J. A., Chlopicki, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842974/
https://www.ncbi.nlm.nih.gov/pubmed/27108697
http://dx.doi.org/10.1038/srep24714

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