Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells

Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. The identification of cancer cell internalizing antigens for drug targeting to the hypoxic tumour niche remains a challenge of high clinical relevance. Here we show that hypoxia down-regulates the surface prot...

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Detalles Bibliográficos
Autores principales: Bourseau-Guilmain, E., Menard, J. A., Lindqvist, E., Indira Chandran, V., Christianson, H. C., Cerezo Magaña, M., Lidfeldt, J., Marko-Varga, G., Welinder, C., Belting, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842985/
https://www.ncbi.nlm.nih.gov/pubmed/27094744
http://dx.doi.org/10.1038/ncomms11371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842985/
https://www.ncbi.nlm.nih.gov/pubmed/27094744
http://dx.doi.org/10.1038/ncomms11371

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