Cargando…
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. The identification of cancer cell internalizing antigens for drug targeting to the hypoxic tumour niche remains a challenge of high clinical relevance. Here we show that hypoxia down-regulates the surface prot...
Autores principales: | Bourseau-Guilmain, E., Menard, J. A., Lindqvist, E., Indira Chandran, V., Christianson, H. C., Cerezo Magaña, M., Lidfeldt, J., Marko-Varga, G., Welinder, C., Belting, M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842985/ https://www.ncbi.nlm.nih.gov/pubmed/27094744 http://dx.doi.org/10.1038/ncomms11371 |
Ejemplares similares
-
Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1
por: Svensson, Katrin J., et al.
Publicado: (2013) -
Tumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity
por: Christianson, Helena C., et al.
Publicado: (2017) -
Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics
por: Indira Chandran, Vineesh, et al.
Publicado: (2019) -
Engineering caveolin-mediated endocytosis in Saccharomyces cerevisiae
por: Zhang, Qian, et al.
Publicado: (2022) -
The Importance of the Stem Cell Marker Prominin-1/CD133 in the Uptake of Transferrin and in Iron Metabolism in Human Colon Cancer Caco-2 Cells
por: Bourseau-Guilmain, Erika, et al.
Publicado: (2011)