Kaempferol stimulates gene expression of low-density lipoprotein receptor through activation of Sp1 in cultured hepatocytes

A high level of plasma low-density lipoprotein (LDL) cholesterol is considered a risk factor for atherosclerosis. Because the hepatic LDL receptor (LDLR) is essential for clearing plasma LDL cholesterol, activation of LDLR is a promising therapeutic target for patients with atherosclerotic disease....

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Detalles Bibliográficos
Autores principales: Ochiai, Ayasa, Miyata, Shingo, Iwase, Masamori, Shimizu, Makoto, Inoue, Jun, Sato, Ryuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842988/
https://www.ncbi.nlm.nih.gov/pubmed/27109240
http://dx.doi.org/10.1038/srep24940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842988/
https://www.ncbi.nlm.nih.gov/pubmed/27109240
http://dx.doi.org/10.1038/srep24940

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