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Age-related impairment of humoral response to influenza is associated with changes in antigen specific T follicular helper cell responses

T follicular helper (T(FH)) cell responses are essential for generation of protective humoral immunity during influenza infection. Aging has a profound impact on CD4(+) T cell function and humoral immunity, yet the impact of aging on antigen specific T(FH) responses remains unclear. Influenza specif...

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Detalles Bibliográficos
Autores principales: Lefebvre, Julie S, Masters, April R, Hopkins, Jacob W, Haynes, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842996/
https://www.ncbi.nlm.nih.gov/pubmed/27109638
http://dx.doi.org/10.1038/srep25051