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Age-related impairment of humoral response to influenza is associated with changes in antigen specific T follicular helper cell responses
T follicular helper (T(FH)) cell responses are essential for generation of protective humoral immunity during influenza infection. Aging has a profound impact on CD4(+) T cell function and humoral immunity, yet the impact of aging on antigen specific T(FH) responses remains unclear. Influenza specif...
Autores principales: | Lefebvre, Julie S, Masters, April R, Hopkins, Jacob W, Haynes, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842996/ https://www.ncbi.nlm.nih.gov/pubmed/27109638 http://dx.doi.org/10.1038/srep25051 |
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