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Whi5 phosphorylation embedded in the G(1)/S network dynamically controls critical cell size and cell fate
In budding yeast, overcoming of a critical size to enter S phase and the mitosis/mating switch—two central cell fate events—take place in the G(1) phase of the cell cycle. Here we present a mathematical model of the basic molecular mechanism controlling the G(1)/S transition, whose major regulatory...
Autores principales: | Palumbo, Pasquale, Vanoni, Marco, Cusimano, Valerio, Busti, Stefano, Marano, Francesca, Manes, Costanzo, Alberghina, Lilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843020/ https://www.ncbi.nlm.nih.gov/pubmed/27094800 http://dx.doi.org/10.1038/ncomms11372 |
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