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Heart Rate Reduction With Ivabradine Protects Against Left Ventricular Remodeling by Attenuating Infarct Expansion and Preserving Remote‐Zone Contractile Function and Synchrony in a Mouse Model of Reperfused Myocardial Infarction

BACKGROUND: Ivabradine selectively inhibits the pacemaker current of the sinoatrial node, slowing heart rate. Few studies have examined the effects of ivabradine on the mechanical properties of the heart after reperfused myocardial infarction (MI). Advances in ultrasound speckle‐tracking allow strai...

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Detalles Bibliográficos
Autores principales: O'Connor, Daniel M., Smith, Robert S., Piras, Bryan A., Beyers, Ronald J., Lin, Dan, Hossack, John A., French, Brent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843531/
https://www.ncbi.nlm.nih.gov/pubmed/27107133
http://dx.doi.org/10.1161/JAHA.115.002989