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Heart Rate Reduction With Ivabradine Protects Against Left Ventricular Remodeling by Attenuating Infarct Expansion and Preserving Remote‐Zone Contractile Function and Synchrony in a Mouse Model of Reperfused Myocardial Infarction
BACKGROUND: Ivabradine selectively inhibits the pacemaker current of the sinoatrial node, slowing heart rate. Few studies have examined the effects of ivabradine on the mechanical properties of the heart after reperfused myocardial infarction (MI). Advances in ultrasound speckle‐tracking allow strai...
Autores principales: | O'Connor, Daniel M., Smith, Robert S., Piras, Bryan A., Beyers, Ronald J., Lin, Dan, Hossack, John A., French, Brent A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843531/ https://www.ncbi.nlm.nih.gov/pubmed/27107133 http://dx.doi.org/10.1161/JAHA.115.002989 |
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