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Validation of Prediction Models for Mismatch Repair Gene Mutations in Koreans

PURPOSE: Lynch syndrome, the commonest hereditary colorectal cancer syndrome, is caused by germline mutations in mismatch repair (MMR) genes. Three recently developed prediction models for MMR gene mutations based on family history and clinical features (MMRPredict, PREMM(1,2,6), and MMRPro) have be...

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Detalles Bibliográficos
Autores principales: Lee, Soo Young, Kim, Duck-Woo, Shin, Young-Kyoung, Ihn, Myong Hoon, Lee, Sung Min, Oh, Heung-Kwon, Ku, Ja-Lok, Jeong, Seung-Yong, Lee, Jae Bong, Ahn, Soyeon, Won, Sungho, Kang, Sung-Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843726/
https://www.ncbi.nlm.nih.gov/pubmed/26044159
http://dx.doi.org/10.4143/crt.2014.288