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Cancer Activation and Polymorphisms of Human Cytochrome P450 1B1
Human cytochrome P450 enzymes (P450s, CYPs) are major oxidative catalysts that metabolize various xenobiotic and endogenous compounds. Many carcinogens induce cancer only after metabolic activation and P450 enzymes play an important role in this phenomenon. P450 1B1 mediates bioactivation of many pr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society of Toxicology
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843978/ https://www.ncbi.nlm.nih.gov/pubmed/27123158 http://dx.doi.org/10.5487/TR.2016.32.2.089 |