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Characterization of CD200 Ectodomain Shedding

We have previously reported the existence of a soluble form of CD200 (sCD200) in human plasma, and found sCD200 to be elevated in the plasma of Chronic Lymphocytic Leukemia (CLL) patients. CLL cells release CD200 at a constitutive level, which could be attenuated partially by ADAM28 silencing. In th...

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Detalles Bibliográficos
Autores principales: Wong, Karrie K., Zhu, Fang, Khatri, Ismat, Huo, Qiang, Spaner, David E., Gorczynski, Reginald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844103/
https://www.ncbi.nlm.nih.gov/pubmed/27111430
http://dx.doi.org/10.1371/journal.pone.0152073