Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABA(A) Receptors

BACKGROUND: Pentobarbital, like propofol and etomidate, produces important general anesthetic effects through GABA(A) receptors. Photolabeling also indicates that pentobarbital binds to some of the same sites where propofol and etomidate act. Quantitative allosteric co-agonist models for propofol an...

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Detalles Bibliográficos
Autores principales: Ziemba, Alexis M., Forman, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844112/
https://www.ncbi.nlm.nih.gov/pubmed/27110714
http://dx.doi.org/10.1371/journal.pone.0154031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844112/
https://www.ncbi.nlm.nih.gov/pubmed/27110714
http://dx.doi.org/10.1371/journal.pone.0154031

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