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Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABA(A) Receptors
BACKGROUND: Pentobarbital, like propofol and etomidate, produces important general anesthetic effects through GABA(A) receptors. Photolabeling also indicates that pentobarbital binds to some of the same sites where propofol and etomidate act. Quantitative allosteric co-agonist models for propofol an...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844112/ https://www.ncbi.nlm.nih.gov/pubmed/27110714 http://dx.doi.org/10.1371/journal.pone.0154031 |