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Generalized Additive Mixed-Models for Pharmacology Using Integrated Discrete Multiple Organ Co-Culture

Integrated Discrete Multiple Organ Co-culture (IDMOC) is emerging as an in-vitro alternative to in-vivo animal models for pharmacology studies. IDMOC allows dose-response relationships to be investigated at the tissue and organoid levels, yet, these relationships often exhibit responses that are far...

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Detalles Bibliográficos
Autores principales: Ingersoll, Thomas, Cole, Stephanie, Madren-Whalley, Janna, Booker, Lamont, Dorsey, Russell, Li, Albert, Salem, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844122/
https://www.ncbi.nlm.nih.gov/pubmed/27110941
http://dx.doi.org/10.1371/journal.pone.0152985