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Generalized Additive Mixed-Models for Pharmacology Using Integrated Discrete Multiple Organ Co-Culture
Integrated Discrete Multiple Organ Co-culture (IDMOC) is emerging as an in-vitro alternative to in-vivo animal models for pharmacology studies. IDMOC allows dose-response relationships to be investigated at the tissue and organoid levels, yet, these relationships often exhibit responses that are far...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844122/ https://www.ncbi.nlm.nih.gov/pubmed/27110941 http://dx.doi.org/10.1371/journal.pone.0152985 |