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The Polymorphisms in LNK Gene Correlated to the Clinical Type of Myeloproliferative Neoplasms

OBJECTIVE: LNK is an adapter protein negatively regulating the JAK/STAT cell signaling pathway. In this study, we observed the correlation between variation in LNK gene and the clinical type of myeloproliferative neoplasms (MPN). METHODS: A total of 285 MPN cases were recruited, including essential...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Fang, Fang, Hu, Yang, Liu, Qian, Bu, Dingfang, Tan, Mei, Wu, Liusong, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844169/
https://www.ncbi.nlm.nih.gov/pubmed/27111338
http://dx.doi.org/10.1371/journal.pone.0154183