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Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients
Insulin-like growth factor (IGF) signalling plays a key role in homing, progression, and treatment resistance in multiple myeloma (MM). In the extracellular environment, the majority of IGF molecules are bound to one of six IGF-binding proteins (IGFBP1-6), leaving a minor fraction of total IGF free...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844248/ https://www.ncbi.nlm.nih.gov/pubmed/27111220 http://dx.doi.org/10.1371/journal.pone.0154256 |