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The influence of dietary sodium content on the pharmacokinetics and pharmacodynamics of fimasartan

A low sodium diet enhances the hemodynamic effect of renin–angiotensin system blockers. It was suggested that the substrates of P-glycoprotein or cytochrome P450 3A4 were reduced on a high sodium diet. This study aimed to investigate the influence of high sodium diet on the pharmacokinetics and phar...

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Detalles Bibliográficos
Autores principales: Gu, Namyi, Cho, Joo-Youn, Shin, Kwang-Hee, Jang, In-Jin, Rhee, Moo-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844258/
https://www.ncbi.nlm.nih.gov/pubmed/27143858
http://dx.doi.org/10.2147/DDDT.S94694