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Effects of a novel ACE inhibitor, 3-(3-thienyl)-l-alanyl-ornithyl-proline, on endothelial vasodilation and hepatotoxicity in l-NAME-induced hypertensive rats

Nitric oxide (NO) is a widespread biological mediator involved in many physiological and pathological processes, eg, in the regulation of vascular tone and hypertension. Chronic inhibition of NO synthase by N(G)-nitro-l-arginine methyl ester (l-NAME) hydrochloride results in the development of hyper...

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Detalles Bibliográficos
Autores principales: Seth, Mahesh Kumar, Hussain, M Ejaz, Pasha, Santosh, Fahim, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844316/
https://www.ncbi.nlm.nih.gov/pubmed/27143859
http://dx.doi.org/10.2147/DDDT.S77761