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α-Mangostin, a Natural Agent, Enhances the Response of NRAS Mutant Melanoma to Retinoic Acid

BACKGROUND: The identification and use of novel compounds alone or in combination hold promise for the fight against NRAS mutant melanoma. MATERIAL/METHODS: We screened a kinase-specific inhibitor library through combining it with α-Mangostin in NRAS mutant melanoma cell line, and verified the enhan...

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Detalles Bibliográficos
Autores principales: Xia, Yun, Chen, Jing, Gong, Chongwen, Chen, Hongxiang, Sun, Jiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844330/
https://www.ncbi.nlm.nih.gov/pubmed/27104669
http://dx.doi.org/10.12659/MSM.898204