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Therapeutic approaches in myelofibrosis and myelodysplastic/myeloproliferative overlap syndromes
The discovery of JAK2(V617F) a decade ago led to optimism for a rapidly developing treatment revolution in Ph(−) myeloproliferative neoplasms. Unlike BCR–ABL, however, JAK2 was found to have a more heterogeneous role in carcinogenesis. Therefore, for years, development of new therapies was slow, des...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844455/ https://www.ncbi.nlm.nih.gov/pubmed/27143923 http://dx.doi.org/10.2147/OTT.S83868 |