Profiling serum bile acid glucuronides in humans: gender divergences, genetic determinants and response to fenofibrate

Glucuronidation, catalyzed by UDP-glucuronosyltransferase (UGT) enzymes detoxifies cholestatic bile acids (BAs). We aimed at i) characterizing the circulating BA-glucuronide (-G) pool composition in humans, ii) evaluating how sex and UGT polymorphisms influence this composition, and iii) analyzing t...

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Detalles Bibliográficos
Autores principales: Trottier, Jocelyn, Perreault, Martin, Rudkowska, Iwona, Levy, Cynthia, Dallaire-Theroux, Amélie, Verreault, Mélanie, Caron, Patrick, Staels, Bart, Vohl, Marie-Claude, Straka, Robert J., Barbier, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844538/
https://www.ncbi.nlm.nih.gov/pubmed/23756370
http://dx.doi.org/10.1038/clpt.2013.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844538/
https://www.ncbi.nlm.nih.gov/pubmed/23756370
http://dx.doi.org/10.1038/clpt.2013.122

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