The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity

BACKGROUND: The overexpression of the chemokine receptor 4 (CXCR4) in different epithelial, mesenchymal, and hematopoietic cancers makes CXCR4 an attractive diagnostic and therapeutic target. However, targeting the CXCR4 receptor with small cyclic pentapeptide-based radiopharmaceuticals remains chal...

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Detalles Bibliográficos
Autores principales: Poschenrieder, Andreas, Schottelius, Margret, Schwaiger, Markus, Kessler, Horst, Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844575/
https://www.ncbi.nlm.nih.gov/pubmed/27112767
http://dx.doi.org/10.1186/s13550-016-0193-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844575/
https://www.ncbi.nlm.nih.gov/pubmed/27112767
http://dx.doi.org/10.1186/s13550-016-0193-8

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