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The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity
BACKGROUND: The overexpression of the chemokine receptor 4 (CXCR4) in different epithelial, mesenchymal, and hematopoietic cancers makes CXCR4 an attractive diagnostic and therapeutic target. However, targeting the CXCR4 receptor with small cyclic pentapeptide-based radiopharmaceuticals remains chal...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844575/ https://www.ncbi.nlm.nih.gov/pubmed/27112767 http://dx.doi.org/10.1186/s13550-016-0193-8 |