A single-domain antibody-linked Fab bispecific antibody Her2-S-Fab has potent cytotoxicity against Her2-expressing tumor cells

Her2, which is frequently overexpressed in breast cancer, is one of the most studied tumor-associated antigens for cancer therapy. Anti-HER2 monoclonal antibody, trastuzumab, has achieved significant clinical benefits in metastatic breast cancer. In this study, we describe a novel bispecific antibod...

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Detalles Bibliográficos
Autores principales: Li, Aifen, Xing, Jieyu, Li, Li, Zhou, Changhua, Dong, Bin, He, Ping, Li, Qing, Wang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844577/
https://www.ncbi.nlm.nih.gov/pubmed/27112931
http://dx.doi.org/10.1186/s13568-016-0201-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844577/
https://www.ncbi.nlm.nih.gov/pubmed/27112931
http://dx.doi.org/10.1186/s13568-016-0201-4

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