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PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model

BACKGROUND: Cyclooxygenase-2 (COX-2) is the inducible isoform of the cyclooxygenase enzyme family. COX-2 is involved in tumor development and progression, and frequent overexpression of COX-2 in a variety of human cancers has made COX-2 an important drug target for cancer treatment. Non-invasive ima...

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Detalles Bibliográficos
Autores principales: Tietz, Ole, Wuest, Melinda, Marshall, Alison, Glubrecht, Darryl, Hamann, Ingrit, Wang, Monica, Bergman, Cody, Way, Jenilee D., Wuest, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844587/
https://www.ncbi.nlm.nih.gov/pubmed/27112768
http://dx.doi.org/10.1186/s13550-016-0192-9