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Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

Virtual memory cells (VM) are an antigen-specific, memory phenotype CD8 T-cell subset found in lymphoreplete, unchallenged mice. Previous studies indicated that VM cells were the result of homeostatic proliferation (HP) resembling the proliferation observed in a lymphopenic environment. Here we demo...

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Detalles Bibliográficos
Autores principales: White, Jason T., Cross, Eric W., Burchill, Matthew A., Danhorn, Thomas, McCarter, Martin D., Rosen, Hugo R., O'Connor, Brian, Kedl, Ross M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844673/
https://www.ncbi.nlm.nih.gov/pubmed/27097762
http://dx.doi.org/10.1038/ncomms11291