Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism

Adipose tissue de novo lipogenesis (DNL) positively influences insulin sensitivity, is reduced in obesity, and predicts insulin resistance. Therefore, elucidating mechanisms controlling adipose tissue DNL could lead to therapies for type 2 diabetes. Here, we report that mechanistic target of rapamyc...

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Detalles Bibliográficos
Autores principales: Tang, Yuefeng, Wallace, Martina, Sanchez-Gurmaches, Joan, Hsiao, Wen-Yu, Li, Huawei, Lee, Peter L., Vernia, Santiago, Metallo, Christian M., Guertin, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844681/
https://www.ncbi.nlm.nih.gov/pubmed/27098609
http://dx.doi.org/10.1038/ncomms11365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844681/
https://www.ncbi.nlm.nih.gov/pubmed/27098609
http://dx.doi.org/10.1038/ncomms11365

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